This study is investigating the effects of slow-wave sleep disruption on major depression.
We are studying the brain mechanisms for Major Depressive Disorder and the correlation between deep sleep and depression.
To investigate, we have participants spend two nights in the sleep lab. One of those nights, we'll play tones while you're sleeping - they're not loud enough to wake you up, just enough to disrupt deep sleep. The other night, we won't play any tones.
The next day, we will evaluate you through various tasks and questionnaires with the goal of studying the effects of the disruption.
Researchers have long believed there could be a correlation between sleep patterns and depression. This study is designed to further investigate the mechanics of the brain and the potential linkage between Major Depressive Disorder and sleep habits.
This study could be for you if you meet the following criteria:
Currently depressed or have no lifetime history of depression
Right-handed
25-50 years old
Participation involves a screening session at the Hospital of the University of Pennsylvania, two overnight stays at the Sleep Center, using a sleep diary and wearing a sleep and activity monitor.
Compensation is provided for completion of study.
There will be no cost to you to participate in the study.